Every year tens of thousands of healthy volunteers are involved in clinical trials in a wide variety of countries. Amongst them “professional volunteers” may expose themselves to serious medical conditions and risk compromising the validity of the scientific results of the trials.  TRUST recommends National Healthy Volunteer Registries to significantly reduce risks for healthy volunteers by monitoring repeated involvement of healthy volunteers in clinical trials. Francois Bompart and Francesca Cavallaro, the authors of the brief, also recommend a monitored cap scheme for financial incentives or a standardised compensation model for participation in clinical trials provides additional protection.

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